Exploring the Lean Phenotype of Glutathione Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles PLOS One 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for Glutathione metabolismrelated proteins expression in BSOtreated Download Scientific Diagram Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo Journal of Biological Chemistry Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma