L Carnitine: Benefits, Uses, Side Effects, and More Early research into L carnitine was often cited as underwhelming, showing negligible changes in muscle carnitine content and fat loss outcomes. However, these findings may have been limited by a short study window The adverse effects of long term l carnitine supplementation on liver and kidney function in rats L Liu, D M Zhang, M X Wang, C Y Fan, F Zhou, S J Wang, L D Kong, 2015 Beneficial effects of l carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose response meta analysis of randomized controlled trials ScienceDirect l Carnitine and synbiotic co supplementation: beneficial effects on metabolic endotoxemia, meta inflammation, and oxidative stress biomarkers in obese patients: a double blind, randomized, controlled clinical trial Food & Function (RSC Publishing)