Medications that Deplete B Vitamins: Why It Happens + How to Prevent Deficiency LivOn Labs Often, people take medications because they are deficient in certain nutrients, which can worsen their deficiencies. Instead, we can take the supplements in the first place. For example: If you're on Ask the Pharmacist: How glutathione is depleted from the body Glutathione depleting Liposome Adjuvant for Augmenting the Efficacy of a Glutathione Covalent Inhibitor Oridonin for Acute Myeloid Leukemia Therapy Journal of Nanobiotechnology Springer Nature Link What are the many health benefits of glutathione?